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GeneExpression Systems, Inc & Appasani Research Conferences and Educational Institute (ARCEI.org)
Jointly Presents

Eighth International
Epigenomics, Stem Cells, Sequencing & SNiPs-2015 Meeting

on ‘Chromatin Methylation to Disease Biology & Theranostics’

Third International
Metabolomics & Microbiome-2015 Symposium

on ' Diabetes, Obesity, Cardiovascular Diseases & Gut Biology'

Date: August 24 – 25, 2015

Venue: In Between Massachusetts Institute of Technology & Harvard University Campuses
777 Memorial Drive at Courtyard Marriott, Cambridge, Massachusetts 02139 USA

“A Unique Theme to Combine Chromatin biology, SNiPs and Diseases with Sequencing Chemistry”

Scope of the Meeting:

The purpose and scope of this 'Metabolomics Symposium' is to provide a forum for the discussion of the current state of the art in emerging branches of metabolic diseases that includes diabetes, obesity and cardiovascular diseases to develop appropriate biomarkers, therapeutics and devises for better diagnosis and treatment.

Metabolomics Symposium-2015 on ‘Diabetes, Obesity, Cardiovascular Diseases &Devices’will bring together young and established clinicians, researchers from  academia and industry (with diverse backgrounds in cardiology, cardiac surgery, endocrinology, diabetes, obesity research, stem cell biology, molecular/cellular biology, drug discovery and other aspects of metabolic disease biology), and discuss the clinical and drug/device discovery strategies in form of keynote lectures, invited talks, short oral, and poster presentations. Dedicated time allowed for presentation of posters, viewing the exhibits, to know the available cutting-edge reagent, devises and services in the field. The conference should be interesting for graduate students, postdoctoral fellows, professors, clinicians from academia and scientists, directors, chief scientific officers and chief executive officers from biopharmaindustry, as well as for anyone interested in studying cardiac and metabolic functions and their associated diseases. Authorities in the field selected and invited as presenting speakers.

Needless to say that Diabetes, Obesity and Cardio-vascular diseases are the major devastating metabolic syndromes in the westernized and developing world. This is the most important venue to bring together mix of quality presentations by high-caliber speakers and a place to exhibit lucrative medical devises. In this meeting we will bring latest innovations in the intersection of obesity, diabetes and cardiovascular diseases. Novel genome-wide, proteomics and systems biology approaches will be discussed to understand the molecular signaling events involved in diseased processes, and subsequently develop novel drug targets. This meeting will also highlight the cell therapy approaches using stem cells especially in the treatment of diabetes, vessel repair and regeneration. Most importantly, the latest devices and their applications in the delivery of insulin, glucose monitoring, vascular stents and synthetic valves will be discussed.

Venue: Courtyard MARRIOTT is a star hotel located on the banks of Charles River in the close vicinity of world renowned Massachusetts Institute of Technology and Harvard University Campuses. This venue is minutes’ walk from the Biotech hub of University Park and Pharmaceutical giants such as: Novartis, Pfizer, Amgen and Takeda.

Note: All the members (except keynote speakers and others who arranged with organizer) who participate in this symposium have to register for the meeting by paying the appropriate registration fee

Click Here For Agenda

Click Here For Brochure

Expected Maximum Capacity:
Target Audience 100
Total Speaker Presentations: 30
Total Poster Presentations: 10
Total Exhibit Booths: 5


Monday, August 24, 2015
8:00 A.M: Registration Open
9.00 AM – 5.00 PM Scientific Sessions

Tuesday August 25, 2015
8:00 A.M: Registration Open
9.00 AM – 4.00 PM Scientific Sessions

Scientific Organizer:

Krishnarao Appasani, PhD., MBA
Founder & CEO
GeneExpression Systems, Inc
Waltham, MA USA

Scientific Committee:
  Laurie Jackson-Grusby, Ph.D.
Assistant Professor of Pathology
Children's Hospital
Harvard Medical School
Boston, MA USA
  Alex Meissner, PhD.
Associate Professor of Stem Cell and Regenerative Biology
Harvard University &
Associate member of the Broad Institute
Cambridge, MA USA
DNA Methylation dynamics in stem cells and development

Key Seession:
Epigenomics & Stem Cells

Diabetes, Obesity,CVD & Microbiome

  • Mechanisms of Chromatin in gene regulation
  • Nuclear dynamics and Methylation Assays
  • Parental imprinting and Histone Deacetylation inhibitors as drugs
  • Epigenetic re-programming in stem cells
  • Cutting-edge sequencing technology; Epigenome Sequencing
  • Epigenetic regulatory processes in diseases & environment
  • Copy Number Variations & Genomo-wide Analysis
  • PharmacoEpigenomics
  • Biology of Diabetes, Obesity & Adipogenesis
  • Detection/Diagnosis using Biomarkers & Imaging
  • Insulin Resistance & Sugar Signaling Mechanisms
  • Novel Insulin Delivery Method
  • Genomic Studies of Complex Metabolic Diseases
  • Multiplex & High throughput Technology Platforms
  • Translational Medicine of Body Weight Regulation
  • Cardiovascular outcome in Diabetes & Obesity
  • Biology of Angiogenesis & Cardiac Diseases
  • Atherosclerosis, Valve Biology and Pathology
  • Molecular Orchestra of Cholesterol Metabolism
  • Detection/Diagnosis using Biomarkers & Imaging
  • Cardiome & Vascular Signaling Mechanisms
  • Genomics/Proteomics Technology Platforms
  • Translational Medicine of Metabolic Syndromes
  • Cardiovascular Repair, Regeneration & Cell Therapy
  • Coronary Intervention through Stents, Angioplasty & Novel Devices
  • Clinical Trials with Novel Drug Targets

Keynote Speaker:

Joel Hirschhorn, MD, PhD.
Concordia Professor of Pediatrics & Genetics         
Children’s Hospital & Harvard Medical School &        
Senior Associate Member and Director
Center for Basic and Translational Obesity Research
Broad Institute of MIT and Harvard
Boston, MA, USA
Title: From human genetics to biology for obesity, height, and other polygenic traits

Other Speakers:

Anand Minajigi, PhD.                                               
Research Fellow in Molecular Biology
Massachusetts General Hospital
Boston MA, USA
Title: Partners of silence: role of Xistinteractome in X inactivation

Bodour Salhia, PhD.
Description: https://mail.google.com/mail/images/cleardot.gifAssistant Professor
Translational Genomics Research Institute
Phoenix, AZ, USA
Title: Circulating DNA Methylation changes associated with metastatic breast cancer

Diane H. Moon, PhD.                                                                       
Postdoctoral Fellow in Hematology/Oncology
Boston Children's Hospital, Harvard medical School
Boston, MA, USA
Title: RegulationofthetelomeraseRNAcomponent(TERC)inbonemarrowfailuredisorders

Corina Shtir, PhD.
Sr. Director of Population Genomics
Thermo Fisher Scientific
Carlsbad, CA, USA
Title:Personalized Medicine based on the population scale programs 

Takeo Kubota, MD, PhD.
Professor of Epigenetics Medicine
University of Yamanashi
Yamanashi, Japan
Title: Therapeutic strategies for mental and neurodevelopmental disorders based on epigenetic mechanism

Yiyi Ma 
Nutrition and Genomics Laboratory
Jean Mayer USDA Human Nutrition Research Center on Aging
Tufts University
Boston, MA, USA
Title: Epigenetics and gene-by-environment interactions

Amar J. S. Klar, PhD.  
Senior Investigator
National Cancer Institute-NIH
Frederick, MD, USA
Title: Selective chromatid segregation epigenetic mechanism explains body laterality development of diverse eucaryotes

Ram Madabhushi 
Postdoctoral Associate
Picower Institute For Learning and Memory
Massachusetts Institute of Technology
Cambridge, MA, USA
Title: A distinct epigenetic signature defines neural cells in familial Alzheimer’s disease

Wesley Brooks, PhD.
Professor of Chemistry                                 
University of South Florida
Tampa, FL, USA
Title:Epigenetics and Autoimmune Diseases: Involvement of the X chromosome, Nucleolus and Polyamines

Lana Saleh, PhD.
Staff Scientist in Chemical biology
New England Biolabs, Inc.
Ipswich, MA, USA
Title: Biochemical characterization of two evolutionary distant ten-eleven translocation enzymes and their utility in 5-methylcytosine sequencing in the genomes at single-base resolution.

Aleksandar Milosavljevic, PhD.
Professor of Molecular and Human Genetics
Baylor College of Medicine
Houston, Texas, USA
Title: Epigenomic deconvolution yields insights into the biology of complex tumor tissues

James L. Sherley, MD., PhD.
Asymmetrex, LLC.
Boston, MA, USA
Title: Outsourcing the wide range evaluation of epigenetic biomarkers for tissue stem cell detection and quantification

Sibaji Sarkar, PhD.
Instructor in Medicine& Genome Institute
Boston University School of Medicine
Boston, MA 02118, USA
Title: Epigenetic regulation of gene silencing in cancer cells

Julie Secombe, PhD.
Assistant Professorof Genetics
Albert Einstein College of Medicine
Bronx-New York, NY,USA
Title:KDM5: More than just a demethylase

David S. Gross, PhD.
Professorof Biochemistry & Molecular Biology
Louisiana State University Health Sciences Center
Shreveport, LA, USA
Title: Hsf1-regulated genes loop, crumple and coalesce into transcriptionally active foci in response to heat shock

  Alison Burkart, PhD.
Research Fellow
Joslin Diabetes Center
Boston, MA, USA
Title: Insulin resistance and its metabolism in mesenchymal progenitor cells

Junco Warren(Junko Shibayama), Ph.D.  
Assistant Professor
Nora Eccles Harrison Cardiovascular Institute
University of Utah
Salt Lake City, USA
Title: Integrated Physiology and Systems Biology of Smyd1                                  

Konstantin Volyanskyy, PhD.                                
Research Fellow
Philips Research North America
Briarcliff Manor NY, USA
Title:A novel phylogeny-based computational framework for heterogeneity assessment and characterization in single cell Sequencing data

Nicolas Rohner, PhD.                                                                      
Postdoctoral Fellow in Genetics
Harvard Medical School
Boston, MA, USA
Title:Cavefish as a model for population differences in metabolic evolution

Koji Hayakawa, PhD.
Graduate School of Agricultural and Life Science
University of Tokyo
Bunkyo-ku, Tokyo, Japan
Title: Epigenetic regulation by nutrient-sensing factors in the degeneration of induced orexin neurons

Michal Stachowiak, PhD.                                        
Professor of Pathology
University of Buffalo School of Medicine
Buffalo, NY, USA 
Title: Global developmental gene programming with FGFR1


Exhibitors are welcome to reserve their booth space early!

Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.

GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com

Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.

For Oral Presentation Abstracts Due By: July 20, 2015
For Poster Presentation Abstracts Due By: August 15, 2015

GeneExpression Systems™ All Rights Reserved 2015