GeneExpression Systems of USA and University of Cambridge of UK
Appasani Research Conferences (ARCEI.ORG)
Jointly Presents

MicroRNAs & Single Molecule Biology Genome Editing Europe - 2014 Symposia

Ninth International
MicroRNAs & NonCoding RNAs Europe 2014 Meeting
On
MicroRNAs/NcRNAs: Biology to Development and Disease

Third International
Single Molecule & Genome Engineering/Editing Europe 2014 Meeting
On
Single Molecule Analysis to Nuclease Technologies

November 3 - 4, 2014

Venue: Peterhouse, University of Cambridge, Cambridge, UK

A Unique Theme Conference & Exhibition in the MicroRNomics & Single Cell Detection

Meeting Place:

The Venue Peterhouse (middle) is the oldest College of the University of Cambridge, founded in 1284 and an institution dedicated to education and research. Throughout its history, Petreans have been at the heart of the political, social and religious controversies that have shaped today’s society. Some of the influential Petreans include: Henry Cavendish, Lord Kelvin, Sir Frank Whittle and Christopher Cockerill, and Nobel Laureates – Sir John Kendrew, Sir Aaron Klug, Archer Martin and Max Perutz , who gave a twentieth century lead in the field of Molecular Biology. Since many centuries it remained as a hub for innovation and successive generations of the brightest young people around the world.

Why do you wait to join for an intellectual gathering in the ‘microRNomics’ & 'Single Moleclue Biology' & 'Genome Editing' arenas at the prestigious college Peterhouse in the Premier University campus!

Click Here for Agenda

MonMonday, November 3, 2014
8:00A.M: Registration Open 
8.45 AM – 6.30 PM Scientific Sessions 

Tuesday, November 4, 2014
8:00A.M: Registration Open 
9.00 AM – 6.00 PM Scientific Sessions

Scientific Organizer:

Krishnarao Appasani, PhD., MBA Founder & CEO GeneExpression Systems, Inc Waltham, MA USA

Key Sessions:

Keynote Speakers:

	René F. Ketting, PhD. Professor & Scientific Director           Institute of Molecular Biology GmbH  University of Mainz Mainz, Germany Title: Priming the next generation with small RNAs
	William C. Skarnes, PhD. Senior Group Leader Sanger Institute-Wellcome Trust Genome Campus Hinxton, Cambridge, UK Title: High-throughput bi-allelic targeting of human iPS cells using CRISPR technology
	Hagan Bayley, PhD.              Professor of Chemical Biology & Chemistry Fellow of Hertford College University of Oxford Oxford, United Kingdom Title: Polymers through pores: single-molecule experiments with nucleic acids, polypeptides and polysaccharides
	Johnathan Lai, PhD. Senior Research Scientist                                          Exiqon Life Sciences, Exiqon A/S Vedbaek, Denmark  Title: Effective and long lasting KD of nuclear retained lncRNA in a broad range of mouse tissues achieved with single stranded LNA enhanced antisense oligonucleotides

Other Speakers:

Micro & NonCoding RNAs		SMB Biology & Genome Editing
	Michaela Frye, PhD. CR-UK Senior Fellow Wellcome Trust – MRC Stem Cell Institute Cambridge, UK Title: Small RNAs regulation and epigenetic modifications in homeostasis and cancer		Steven F. Lee, PhD. Royal Society Research Fellow in Chemistry University of Cambridge Cambridge, Cambridgeshire, UK Title: Single molecule analysis with super resolution imaging
	Jan Oxholm Gordeladze, PhD. Professor of Biochemistry University of Oslo Oslo, Norway Title: Epigentic factors involved in the “mineralizing/demineralizing” capability of cell phenotypes: Histone deacetylases (HDACs/Sirts), transcription factors (TFs), microRNAs, and vitamin K2 (MK-7/MK-4)		Katsuyuki Shiroguchi, PhD. Lab Leader &Principle Investigator RIKEN Center for Integrative Medical Sciences Tsurumi-ku Yokohama Kanagawa,Japan Title: Accurate system-wide gene expression analysis with single molecule resolution by using molecular barcoding
	Peter Leedman, PhD. Professor & Director Designate Harry Perkins Inst. of Medical Research Nedlands, Australia Title:miR-7: a potent tumor suppressor and candidate for replacement therapy		Lorenz A. Fenk, PhD Student                      Cell Biology/Dr. Mario de Bono’s Lab MRC-Laboratory of Molecular Biology Cambridge, UK Title: Ctrl+Alt+Delete: editing the genome of a worm
	Daniela Taverna, PhD. Associate Professor of Molecular Biology University of Turin  Torino, Italy Title: miR-214 in melanoma progression		Satoshi Habuchi, PhD. Associate Professor Biological, Environmental & Engineering King Abdullah University of Science and Technology Thuwal, Kingdom of Saudi Arabia Title: Multi-parametric analysis of single-molecule diffusion and conformational dynamics
	Gracjan Michlewski PhD. MRC Career Development Award Fellow TheWellcome Trust Centre for Cell Biology University of Edinburgh Edinburgh, Scotland, UK Title: Lin28a regulates neuronal differentiation and controls miR-9 production		Gerald Schwank, PhD. Researcher at Hubrecht Institute, TheNetherlands & Assistant Professor, ETH Zurich, Switzerland Title: Genome editing by CRISPR/Cas9 in intestinal stem cell organoids
	Stefan Erkeland, PhD. Assistant Professor of Hematology Erasmus University Medical Center Rotterdam, The Netherlands Title: Deregulation of miR-139-3p and miR-199a-3p drives leukemic transformation of interstrand cross-link induced bone marrow failure		Takuma Sugi, PhD.                                                   Assistant Professor & JST PRESTO Researcher Institute for Integrated Cell-Material Sciences Kyoto University, Kyoto, Japan Title: Regulation of gene expression and behavior by genome editing technology in C. elegans
	Stephen G. Maher, PhD. Senior Lecturer in Biomedical Science University of Hull, Hull, United Kingdom  &Adjunct Associate Professorof Surgery  Trinity College Dublin-St. James’ Hospital, Ireland Title: MicroRNA mediated regulation of sensitivity to chemoradiotherapy in oesophageal adenocarcinoma		Morten Frodin, PhD. Professor & Group Leader Biotech Research & Innovation Center University of Copenhagen Copenhagen, Denmark Title: High-efficiency genome editing by combining FACS with 2A-coupling of fluorescent proteins to ZFNs or Cas9
	Guy Wheeler, PhD. Senior Research Associate University of East Anglia Norwich, UK Title: The function of microRNA-140 in cartilage development and osteoarthritis		David Suter, MD, PhD. SNSF Assistant Professor of Bioengineering EcolePolytechniqueFederale de Lausanne (EPFL) Lausanne,Switzerland Title: Transcription at the single cell level
	Cecilia Mannironi, PhD. Researcher CNR-Institute of Molecular Biology & Pathology SapienzaUniversity of Rome Rome, Italy Title: miR-135a and miR-124 in Stress Response		Laszlo Puskas, PhD., DSc.              Chief Executive Officer Avidin Biotechnology Ltd. Szeged, Hungary & Professor of Genetics Hungarian Academy of Sciences, Szeged, Hungary Title: Digital PCR to determine the number of transcripts from single neurons after patch-clamp recording
	Nicola Valeri, MD., PhD. Team Leader in Molecular Pathology The Institute of Cancer Research Belmont, Sutton Surrey, United Kingdom  Title: Role of miR-135 b in the cancer progression		Holger Erfle, PhD. Head of ViroQuant-CellNetworks                   University of Heidelberg-Bioquant Heidelberg, Germany Title: High throughput screenings at single molecule level
	Bassam Badran, PhD. Professor of Biochemistry                              Faculty of Sciences-Lebanese University Hadath Beirut, Lebanon Title: Role of microRNAs in the expression of the human IL-21		Pétur O. Heidarsson, PhD.                          Postdoctoral Research Fellow University of Copenhagen Copenhagen, Denmark Title:Calcium-dependent folding and misfolding pathways in a neuronal calcium sensor
	Xavier Loyer, PhD. Researcher in Atherosclerosis Markers Team INSERM U970-PARCC University of Paris Descartes Paris, France Title: Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice		Andrea Soranno, PhD. Postdoctoral Fellow in Biochemistry University of Zurich Zurich, Switzerland Title: Probing the polymer properties of intrinsically disordered proteins with single-molecule spectroscopy
	Aida Martinez-Sanchez, PhD.                     Research Associate in Medicine Division of Diabetes, Endrocrinology&Metabolism Imperial College London, United Kingdom Title: Role of miRNAs in the articular chondrocyte: new insights into miR-145 function		Yasutaka Mizoro, PhD. Assistant Professor CiRA, Kyoto University Kyoto, Japan Title: Transcriptome analysis of iPS cells and differentiation cells using single cell RNA sequencing
	Blanche Schroen, PhD. Researcher in Center for Heart Failure Research CARIM School for Cardiovascular Diseases Maastricht University Maastricht, The Netherlands Title: Cardiac immune activation in heart failure – a causative role for the pro-inflammatory microRNA-155		Beata Klejevskaja, PhD Student Molecular Medicine, Faculty of Medicine National Heart and Lung Institute Imperial College London London, UK Title: Single molecule FRET studies of G-quadruplex structure formed in DNA mini-circles
	Oluf Dimitri Røe, MD., PhD. Oncologist&Researcher SykehusetLevanger Cancer Hospital Levanger, Norway &Norwegian University of Science and Technology Trondheim, Norway Title: Early diagnosis of lung cancer and mesothelioma by microRNA-where are we?		Radislav Sedlacek, PhD. Associate Professor Czech Centre for Phenogenomics Institute of Molecular Genetics ASCR, v. v. i Praha, Czech Republic Title: Use of TALENs and CRISPR editing tools for generating transgenic animals
	Jennifer Winter, PhD. Group Leader in Inst. of Human Genetics University Medical Centre Mainz Mainz,Germany Title: miR-379-410 cluster regulation in neurogenesis and neuronal migration		Mark C. Leake, PhD. Professor & Director  Biological Physical Sciences Institute University of York, York, UK Title: Probing DNA interactions with proteins at the single-molecule level in cellulo, in vitro, and in silico
	Agnieszka Podolska, PhD. Postdoctoral Scientist BRIC-University of Copenhagen Copenhagen, Denmark Title: miRNA expression and function in C. elegans		Hannu Myllykallio, PhD. Research Director INSERM-CNRS-EcolePolytechnique Palaiseau, France Title: Structural and cellular dynamics of archaeal nucleases
	Hussein Fayyad-Kazan, PhD.  Researcher inExperimental Hematology Jules Bordet Institute-Universitélibre de Bruxelles Bruxelles, Belgium Title: A microRNA profile of human CD8 positive regulatory T lymphocytes and characterization of the effects of microRNAs on Treg cell associated genes		Nikos Hatzakis, PhD. Assistant Professor of Chemistry Nano-Science Center, University of Copenhagen Copenhagen, Denmark Title: The art of understanding structure function correlations of membrane related enzymes by observing one molecule at a time
	Sofie Sølvsten Sørensen, MD., PhD. Student Nordsjællands Hospital Copenhagen University Hospital Hillerød, Denmark Title: miRNA expression profiles as diagnostic biomarkers of acute ischemic stroke		Sergio Garcia-Manyes, PhD. Lecturer of Physics & EPSRC Fellow Kings College London Strand Campus London, UK Title: Mechanical protein folding at the single molecule level
	Karin Ekström, PhD.                                    Researcher in Biomaterials University of Gothenburg Göteborg, Sweden Title: Extracellular miRNA, exosomes and cell-cell communication		Victoria Birkedal, PhD.                                 Assistant Professor of Single Molecule Biophysics INano Center-Aarhus University Aarhus, Denmark Title: Structural dynamics of nucleic acids studied by single molecule FRET
	Li Zeng, PhD. Principle Investigator Neural Stem Cell Research Lab National Neuroscience Institute Singapore Title: Deciphering function and regulation of miRNA in neural differentiation in the developing cerebral cortex		Timothy Craggs, PhD. Postdoctoral Research Assistant in Physics University of Oxford-Clarendon Labs Oxford, UK Title: Single-molecule FRET for dynamic structural biology: DNA Polymerase I structure and mechanism with angstrom precision
	Amy Lewis, PhD. Post-doctoral Researcher  Barts and The London Medical School Queen Mary College, London University London, UK Title: Extracellular microRNAs in stricturing Crohn’s disease		Tudor A. Fulga, PhD. Associate Professor of Genome Biology                                             Institute of Molecular Medicine University of Oxford, Oxford, UK Title: Deciphering miRNA-target regulation by site-specific genome engineering
	Dr. Rodrigo M. Maza Researcher in Experimental Neurology Unit Hospital Nacional de Parapléjicos Toledo, Spain Title: MicroRNAs in the pathophysiology and treatment of the spinal cord injury		Yueng Tchern Lenn, PhD. Postdoctoral Research Assistant in Biological & Chemical Sciences Queen Mary University of London London, UK Title: Organization of energy production in bacterial cells
	Claudia Piovan, PhD. Researcher in Experimental Oncology Foundazione IRCCS InstitutoNazionaledeiTumori Milan, Italy Title: Involvement of microRNAs in HER2-driven breast cancer.		Rodolphe Marie, PhD. Associate Professor of Micro & Nanotechnology Technical University of Denmark 2800 KongensLyngby, Denmark Title: Mapping single DNA molecules to the human genome in a nanofluidicdevice
	Anke Nijhuis, PhD Student Barts and The London Medical School Queen Mary College, London University London, UK Title: MicroRNAs expression profiling of colorectal cancer tissue and cell lines in low oxygen tension		Gautam V. Soni, PhD.                                  Associate Professor Raman Research Institute Bangalore,India Title: Measuring physical properties of nucleosomes, one molecule at a time
	Juliane Braun, PhD. Researcher at Inst. of Molecular Medicine Martin Luther University Halle-Wittenberg Halle, Germany Title: Rapid and comprehensive identification of regulatory microRNAs by miTRAP		Joon Won Park, PhD. Head & Professor of Chemistry Pohang University of Science and Technology (POSTECH) Pohang. Gyeongbuk, Korea Title: Reading Single DNA Bases with Atomic Force Microscopy and Detecting a DNA Biomarker of a Few Copies without Amplification
	Hongbin Zhang, PhD.                                   Associate Professor of Biomedical Sciences University of Copenhagen Copenhagen N, Denmark Title: microRNA regulation of brown adipogenesis
	Carlos P. Fitzsimons, PhD. Assistant Professor of Neuroscience Swammerdam Institute for Life Sciences University of Amsterdam Amsterdam, The Netherlands Title: From microRNA profiling to target regulation by cooperative microRNA action. Lessons learned from an experimental model of epilepsys
	Victor X. Jin, PhD. Dept of Molecular Medicine University of Texas Health Sciences Center San Antonio, TX, USA Title: MicroRNA-31 predicts the presence of lymph node metastases and survival in lung adenocarcinoma patients
	Steffen Panzner, PhD.                                  Managing Director Lipocalyx GmbH Halle, Germany Title:Transfection: Viral and Synthetic Techniques Converge; High-Tech Polymers Leveraging Viral Biophysics Can Enhance the Transfection of Nucleic Acids

* Presenting Speaker names, title and times are subject to change.
Host organization, organizer, or scientific committee does not take any kind of responsibility.

Exhibitors are welcome to reserve their booth space early!

Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.

GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com
www.expressgenes.com

Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.