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GeneExpression Systems, Inc & Appasani Research Conferences and Educational Institue (ARCEI.ORG)
Jontly Presents
Therapeutics Discovery Symposia USA - 2014
Three Theme Meetings at One Location
RNAi, MicroRNAs & Single Cell Biology - 2014 Meeting
On
'RNA Interference, MicroRNAs & SCB: Biochemistry to Drugs &Therapeutics'
&
Stem Cells & Cell Signaling - 2014 Meeting
On
'Assays to Regenrative Medicine , Tissue Engineering & Therapeutics'
&
Genome Engineering & Genome Editing - 2014 Meeting
On
'Synthetic Biology to Zinc Finger Nucleases, TALENs & CRISPRs Regulation'
Date: MAY 5 – 6, 2014
Venue: Hilton Garden Inn, 420 Totten Pond Road, Waltham, MA 02451, USA
| Expected Maximum Capacity of each Meeting |
| Target Audience |
100 |
| Total Speaker Presentations: |
30 |
| Total Poster Presentations: |
10 |
| Total Exhibit Booths: |
10 |
Click Here For Agenda
Monday, May 5, 2014
8:00 AM: Registration Open
9:00 AM - 6:30PM
Scientific Sessions
Tuesday, May 6, 2014
8:00 A.M: Registration Open
9:00 AM - 4:30PM
Scientific Sessions
Click Here For: SCOPE OF THE MEETING
SCOPE OF THE MEETING:
The purpose and scope of this Therapeutics Discovery Symposia USA - 2014 (on May 5-6, 2014) is to provide a forum for the discussion of the current state of the art of rapidly evolving RNA interference, MicroRNAs, Stem Cells and Genome Editing highly interdisciplinary emerging fields in biotechnology. This will consists of three parallel theme meetings:
1.RNA interference & MicroRNAs-2014: This is our 11th international theme conference continuously held in the first week of May in Waltham/Boston, Massachusetts, USA. Emeritus Professor Arthur Pardee of the Harvard University Medical School inaugurated our first meeting in May 2003. Since then, pioneers in both RNAi& MicroRNAs fields including: Nobel laureates Drs. Craig Mello, Richard Roberts and Professors Gary Ruvkun, David Bartel, Carlo Croce, and many more have given keynote speeches. RNAi and MicroRNAs are the “biology’s Big Bang” and we are igniting the spirit of both RNomics & microRNomics in order to understand the biology of gene-silencing and to develop innovative products based on this technology platform.
2. Stem Cells & Cell Signaling-2014: This is our 7th international theme conference continuously held in either West Coast or East Coast of USA. Nobel Laureate Paul Berg of the Stanford University Medical School inaugurated our first meeting in 2006. Since then, pioneers in both Stem Cells & Tissue Engineering fields including: Nobel Laureate Elizabeth Blackburn, John Gurdon, and Professors Gail Martin, Irving Weissman, Ole Issacson, Helen Blau, and many more have given keynote speeches. Stem cells have great utility not only in cell biology and clinically for treatment of diseases, but also in drug discovery and development. Therefore, this meeting will focus on developmental aspects to signaling mechanisms and genome-scale mapping of DNA methylation in pluripotency as well highlights the stem cell based-therapeutics from biotech industry and associated novel reagent/assay/tool developments from reagent companies.
3. Genome Engineering & Genome Editing-2014: This is our first international theme conference on Genome Editing. However, part of the theme ‘Genome Engineering’ organized earlier as ‘Frontiers in Synthetic Biology’ meeting since 2008. Nobel Laureate Jack Szostack of the Harvard Medical School inaugurated our first meeting in 2008. Since then, pioneers in synthetic biology including: Drs. Clyde Hutchison III, Wilfried Weber, Pam Silver, Jim Collins, and many more have given keynote speeches. This meeting covers the topic of genome editing mediated by small to long non-codingRNAs, engineering of Nucleases, TALENs and CRISPRs system.
In this international meeting, prominent researchers (Developmental biologists, cell biologists, geneticists, molecular biologists, computational biologists, neurobiologists, clinicians, chemists and physicists) from both academia and industry will gather and discuss the applications in form of keynote lectures, invited talks, short oral, and poster presentations.
Venue: Hilton Garden Inn is a star hotel located on the Rt. 95/128 high-tech corridor in Waltham, a western suburb of Boston/Cambridge, which is well connected by bus transportation.
Note: All the members (except keynote speakers and others who arranged with organizer) who participate in this symposium have to register for the meeting by paying the appropriate registration fee
Scientific Organizer:
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Krishnarao Appasani, PhD, MBA
Founder & CEO
GeneExpression Systems, Inc
Waltham, MA USA
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Keynote Speakers:
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Kai W. Wucherpfennig, MD, PhD.
Professor of Neurology, Harvard Medical School
Professor of Cancer Immunology & AIDS
Dana-Farber Cancer Institute
Boston, MA, USA
Title: In vivo discovery of targets for cancer immunotherapy |
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James J. Collins, DPhil.
William F. Warren Distinguished Professor
HHMI Investigator, Boston University &
Wyss Institute of Harvard University
Boston, MA, USA
Title: Life Redesigned: The Emergence of Synthetic Biology |
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Kevin C. Eggan, PhD.
Associate Professor of Stem Cell & Regenerative Biology
& Investigator, Howard Hughes Medical Institute
Member, Harvard Stem Cell Institute
Harvard University &
Cambridge, MA, USA
Title: Biology of stem cell programming and reprogramming |
Other Speakers: TBA
RNAi, MicroRNAs & SCB Speakers: |
Stem Cell Speakers: |
Genome Engineering &
Genome Editing Speakers: |
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Susanna Obad, PhD.
Manager, Drug Discovery
Santaris Pharma A/S
Hørsholm, Denmark
Title: Targeting of microRNAs for therapeutics |
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Sanjeev Gupta, MD.
Professor of Medicine &
The Eleazar & Feige Reicher Chair in Translational Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
Title: Mechanisms in hepatic differentiation of pluripotent stem cells offer therapeutic applications for candidate human conditions |
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Chad Cowan, Ph.D.
Associate Professor
Center for Regenerative Medicine
Massachusetts General Hospital
Boston, MA, USA
Title: A TALEN genome-editing system for generating human stem cell-based disease models |
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Mingyi Xie, PhD.
Post-doctoral Fellow in Dr. Joan Steitz’s Lab, Yale University
New Haven, CT, USA
Title: Mammalian 5′-capped microRNA precursors that generate a single microRNA |
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Ken Rando
BioSpherix, Ltd.
Lacona, New York, USA
Title: Better manufacturing practice for cell therapies |
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Hiroshi Ochiai, PhD.
Assistant Professor of Mathematical & Life Sciences, Graduate School of Science
Hiroshima University
Higashi-Hiroshima, Japan
Title: TALEN-mediated single-base-pair editing reveals the functional significance of an intergenic single nucleotide variant |
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Ryan M. O'Connell, PhD.
Assistant Professor of Pathology
University of Utah School of Medicine
Salt Lake City, Utah, USA
Title: MicroRNAs regulate chronic inflammation during aging |
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Paul Feinstein, PhD.
Associate Professor of Biology
Hunter College, City University of New York
New York, NY, USA
Title: Quantitative RT-PCR-based screening in mouse ES cells |
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Florian Lienert, PhD.
Postdoctoral Fellow in Systems Biology
Harvard Medical School
Boston, MA, USA
Title: Tools for genetic circuit engineering in mammalian cells |
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Christopher M. Hammell, PhD.
Assistant Professor
Watson School of the Biological Sciences
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY, USA
Title: LIN-42, the Caenorhabditiselegans PERIOD homolog, negatively regulates microRNA biogenesis |
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David Brafman, PhD. MBA
Kaehr Stem Cell Investigator
University of California, San Diego
La Jolla, CA, USA
Title: Analysis of SOX2-expressing cell populations derived from human pluripotent stem cells |
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Ayal Hendel, PhD.
Myotonic Dystrophy Foundation Fellow
Stanford University School of Medicine
Stanford, CA, USA
Title: Policing the Editor: Quantifying Genome Editing Outcomes at Endogenous Loci using SMRT Sequencing |
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Shobha Vasudevan, PhD.
Assistant Professor of Medicine
MGH Cancer Center-Harvard Medical School, Boston, MA, USA
Title: A specialized mechanism of microRNA-mediated translation in cellular quiescence |
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Albert Q. Lam, MD.
Associate Physician & Instructor in Medicine
Brigham and Women's Hospital
Harvard Medical School
Boston, MA, USA
Title: Directed differentiation of human pluripotent stem cells into cells of the kidney lineage |
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Jun Jiang, MD. & PhD.
Instructor in Cell & Developmental Biology,
UMASS Medical School
Worcester, MA, USA
Title: XIST-mediated trisomy correction in Down syndrome stem cellsy |
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Carla P. Concepcion
PhD Student in Cancer Biology & Genetics, Memorial Sloan Kettering Institute
New York, NY, USA
Title:Investigating the biological functions of the miR-34 family of microRNAs |
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Karl Willert, PhD.
Assistant Professor & Director
Human Embryonic Stem Cell Core Facility
University of California, San Diego
La Jolla, CA, USA
Title: Regulation of pluripotency by Wnt signaling |
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Fei Ann Ran
PhD Student in Dr. Feng Zhang’s Lab
The Broad Institute &
Massachusetts Institute of Technology
Cambridge, MA, USA
Title: Mammalian genome engineering with the CRISPR/Cas system |
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Jesse R. Zamudio, PhD.
Postdoctoral Fellow in Dr. Phil Sharp’s Lab, David H. Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology
Cambridge, MA, USA
Title: Argonaute-bound small RNAs from promoter-proximal RNA Polymerase II |
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Yan-Ru Lou, PhD.
Researcher in Pharmacy
University of Helsinki
Helsinki, Finland
Title: 3D culture of human pluripotent stem cells in nanofibrillar cellulose hydrogel |
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Andrew Geall, PhD.
RNA Vaccine Platform Technology Leader
Novartis Vaccines and Diagnostics
Cambridge, MA,USA
Title: Using synthetic biology and self-amplifying mRNA vaccines to facilitate a rapid response to pandemic influenza |
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J. Michael French
President & CEO
Marina Biotech, Inc.
Bothell, WA, USA
Title: Smartcles-based RNAi delivery |
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Jae-Won Shin, PhD.
Postdoctoral Fellow in Engg.& Applied Sciences
Harvard University
Cambridge, MA, USA
Title:Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells |
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Izuho Hatada, PhD.
Professor of Genome Science
Institute for Molecular and Cellular Regulation, Gunma University
Maebashi, Japan
Title: Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system |
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Sam Gu, PhD.
Assistant Professor of Molecular Biology
Rutgers University
Piscataway, NJ, USA
Title: Nuclear RNAi-dependent transcriptional silencing of retrotransposons in C. elegans |
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Hui Zhang, PhD.
Associate Professor of Chemistry
University of Nevada
Las Vegas, NV, USA
Title: Roles of Sox2 in epigenetic regulation of stem cells and cancer cells |
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Ankur Dalia, PhD.
Postdoctoral Fellow in Molecular Biology
HHMI at Tufts University School of Medicine
Boston, MA, USA
Title: Multiplex genome editing by natural transformation in bacteria |
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Larry McReynolds, PhD.
Director of RNA Biology
New England Biolabs, Inc.
Ipswich, MA, USA
Title: MicroRNA detection using SplintRTM ligase |
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Wa Xian, PhD.
Assistant Professor
The Jackson Laboratory for Genomic Medicine
Farmington, CT 06032, USA
Title: p63+/Krt5+ distal airway stem cells are essential for lung regeneration |
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Claes Gustafsson, PhD.
Founder & Chief Commercial Officer
DNA 2.0, Inc.
Menlo Park, CA, USA
Title: Engineering biology using gene synthesis and machine learning |
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John Paul Pezacki, PhD.
Sr. Research Officer in Life SciencesNational Research Council of Canada
Ottawa ON, Canada
Title: siRNA delivery |
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Sei Kameoka
Senior Associate Scientist
Center for Cell Biology Research
Biogen Idec
Cambridge, MA, USA
Title: High throughput screenings for teratogens using human pluripotent stem cells |
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Fernando J. Bustos, PhD.
Researcher in Pathology and Medical Biology
University Medical Center Groningen
Groningen, The Netherlands
Title: Targeted epigenetic silencing of PSD95 gene expression rescues dendritogenesis in hippocampal neurons |
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Malia Potts, PhD.
Postdoctoral Fellow in Cell Biology
University of Texas, Southwestern Medical School
Dallas, TX, USA
Title: Broad scale mode-of-action annotation of miRNAs and chemical compounds by Functional Signature Ontology (FuSiOn) |
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Dodanim Talavera-Adame, MD, MSc, PhD.Research Scientist I - Instructor
Regenerative Medicine Institute &
Cedars-Sinai Medical Center,
Los Angeles, CA, USA
Title: Bone Morphogenetic Protein-2/-4 Upregulation Promoted by Endothelial Cells in Coculture Enhances Mouse Embryoid Body Differentiation |
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Victoria Bedell, MD/PhD Student
Mayo Clinic Cancer Center
Rochester, MN,USA
Title: In vivo genome editing using a high-efficiency TALEN system in Zebrafish |
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Marcelo Mori, PhD.
Assistant Professor of Biophysics
Federal University of São Paulo
Sao Paulo, Brasil
Title: Short cuts to prolong health span |
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David Edgell, PhD.
Associate Professor of Biochemistry
& CIHR New Investigator
University of Western Ontario
London, ON, Canada
Title: Monomeric nuclease domains for genome editing |
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Juan A. Gallego, MD, MS
Psychiatrist, The Zucker Hillside Hospital & Assistant Professor of Psychiatry
Hofstra North Shore-LIJ School of Medicine
Glen Oaks, NY, USA
Title: Differential expression of microRNAs in cerebrospinal fluid in patients with schizophrenia |
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Tomomi Aida, PhD.
Assistant Professorof Molecular Neuroscience
Tokyo Medical and Dental University
Tokyo, Japan
Title:In vivo genome editing |
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Hakim Djaballah, PhD.
Director, High-Throughput Drug Screening Facility
Memorial Sloan Kettering Cancer Center
New York, NY, USA
Title: Comparative analysis of RNAi screening technologies at genome-scale |
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Xiaohong Zhu, PhD.
ResearchAssociate in Horticulture and Landscape Architecture
Purdue University
West Lafayette, IN, USA
Title: CRISPR/Cas induced gene editing in Arabidopsis plants |
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Irene A. Chen, MD, PhD.
Assistant Professor of Biochemistry
University of California
Santa Barbara, CA, USA
Title: Evolutionary networks for smallRNAs |
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Aris N. Economides, PhD.
Senior Director
Genome Engineering Technologies Group
Regeneron Pharmaceuticals, Inc.
Tarrytown, NY, USA
Title: Genome engineering approaches for large genomic region exchanges and conditional alleles |
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Susan Magdaleno, PhD.
R&D Sr. Manager, Scientist
ThermoFisher, Inc.
Austin, TX, USA
Title: Using NGS with RNA Ampliseq™ to correlate siRNA transfection with knockdown in single cells |
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Arumugham Raghunathan, PhD.
Head of US Business Development
Cell Engineering & Cell Line Products
Horizon Discovery Ltd., Cambridge, UK
Title:Genome Editing as an emerging technology to functionalize the human genome and accelerate targeted drug discovery |
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Thomas Z. Armel, Ph.D.
Director of Technology & Founding Partner
Quantitative Scientific Solutions LLC
Washington DC, USA
Title: Applications for genome engineering technologies |
* Presenting Speaker names, title and times are subject to change.
Host organization, organizer, or scientific committee does not take any kind of responsibility.
| Key Topics: |
| RNAi, MicroRNAs & SCB-2014 |
Stem Cells -2014 |
Genome Engg/Genome Editing-2014 |
- The Genetics of RNAi and microRNAs
- RNAi, Oligos delivery in vivo, in vitro
- microRNAs and their diverse roles in biology & disease
- Computational and Disease Biology of miRNAs
- High throughput genome-wide screenings
- Single cell qPCR in Stem cells, tumor cells
- Fluorescence Spectroscopy & Correlation Microscopy
- Single Molecule Genomics & Imaging in live cells
- Atomic (Single Molecule) Force Microscopy
- Fluorescent proteins and in vivo Analysis
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- Self-renewal and Maintenance
- Stem Cells Propagation Techniques & Novel Reagents
- Biopolymer Applications in Tissue Engineering
- Epigenetic & Transcriptional Controls of Stem Cells
- Signaling Mechanisms in Stem Cells
- Tissue Organ Culture and Transplantation
- Applications of Stem Cells to Human Diseases
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- Biology, Design and Delivery Strategies of Nucleases (ZFNs & TALENs)
- Zinc Finger Nucleases & TALENs-based genome editing in model organisms
- Generation of ZFN/TALEN-mediated knockout animals and cell lines
- Epigenetic/Epigenomic editing in stem cells
- RNA-guided genome engineering with CRISPRs
- Engineering Genomes & Organelle using Synthetic Biology
- Gene Engineering & Targeting with Transposons,
- Integrases, Meganucleases & RNA-guided Endonucleases (RGENs)
- Genome Surgery to Engineering using designer nucleases
- High throughput genome editing & Therapeutic applications
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Exhibitors are welcome to reserve their booth space early!
Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.
GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com
www.expressgenes.com
Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.
Oral Presentation Submission by February 10, 2014
Poster Abstract Submission by April 20, 2014
Email your abstract (100-200 words in word format) to: genexpsys@expressgenes.com
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